Zebrafish Disease Models

Zebrafish (Danio rerio) has been extensively widely used as an animal model in various fields of biomedical research. The transparency of the zebrafish embryo enables real-time visualization of the development and morphogenesis of almost all of its tissues and organs. Zebrafish are amenable to genetic manipulation, for which advanced genetic and molecular techniques are constantly being introduced. A pair of adult zebrafish can produce hundreds of eggs in a single clutch, and the resulting embryos and larvae are sufficiently small that they can be housed in 96-well or 384-well plates, allowing phenotypic analysis by high-throughput microscopy and behavioral analysis systems.

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Thursday, July 24, 2025, 2:03 AM

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